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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Cardiovascular complications of obstructive sleep apnea syndrome: evidence from children

Rakesh Bhattacharjee1, Leila Kheirandish-Gozal, Giora Pillar

  • 1Kosair Children's Hospital Research Institute, Louisville, KY 40202, USA.

Progress in Cardiovascular Diseases
|March 3, 2009
PubMed

Insights

Obstructive Sleep Apnea Syndrome (OSAS) in children disrupts sleep and gas exchange. This review details cardiovascular complications in pediatric OSAS, impacting current and future heart health.

Area of Science:

  • Pediatric Sleep Medicine
  • Cardiovascular Health
  • Respiratory Medicine

Background:

  • Obstructive Sleep Apnea Syndrome (OSAS) is a prevalent pediatric condition.
  • It involves upper airway occlusion during sleep, causing gas exchange disturbances and altered sleep patterns.
  • Emerging evidence links pediatric OSAS to various end-organ morbidities, particularly cardiovascular issues.

Purpose of the Study:

  • To review and present cardiovascular complications associated with pediatric OSAS.
  • To discuss the underlying mechanisms contributing to these complications.
  • To explore the potential long-term implications for cardiovascular health in affected children.

Main Methods:

  • Literature review of studies on pediatric OSAS and cardiovascular outcomes.
  • Synthesis of findings on specific cardiovascular complications.
  • Analysis of proposed pathophysiological mechanisms.

Main Results:

  • Pediatric OSAS is associated with significant cardiovascular morbidities.
  • These complications can manifest during childhood and persist into adulthood.
  • Mechanisms involve intermittent hypoxia, sleep fragmentation, and autonomic dysfunction.

Conclusions:

  • Cardiovascular complications are a critical concern in pediatric OSAS.
  • Early identification and management are crucial for mitigating long-term cardiovascular risks.
  • Further research is needed to fully elucidate the impact and optimize treatment strategies.

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