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Published on: March 2, 2017
Comparison of pregnancy outcomes in elective single blastocyst transfer versus double blastocyst transfer stratified
Christine M Mullin1, M Elizabeth Fino, Sheeva Talebian
1New York University Fertility Center, New York University, New York, New York 10016, USA. christine.mullin@gmail.com
Objective:
To determine whether there is a difference in pregnancy outcomes, stratified by age, between women undergoing elective single blastocyst transfer (eSBT) versus those undergoing double blastocyst transfer (2BT).
Design:
Retrospective analysis.
Setting:
University IVF center.
Patient(S):
A total of 1,141 nondonor IVF cycles in women aged <40 years from January 2004-March 2007.
Intervention(S):
None.
Main Outcome Measure(S):
Eggs retrieved, embryos cryopreserved, implantation rates, clinical pregnancy rates (PR), live birth rates (LBR), spontaneous abortion rates (SAB).
Result(S):
Pregnancy outcomes in 52 cycles of women <40 years of age who underwent eSBT were compared with 1,086 cycles of women who underwent 2BT in fresh IVF cycles from January 2004-March 2007. Overall, the eSBT was associated with a statistically significant 92% reduction in the twinning rate (from 25%-2%) while maintaining a high clinical PR (63% in the eSBT group vs. 61% in the 2BT group).
Conclusion(S):
Women who are <40 years of age undergoing nondonor fresh IVF cycles can electively choose to transfer a single blastocyst for the purpose of significantly reducing their risk of multiples without compromising their PR.
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