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Updated: Jun 25, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Hyperperfusion syndrome following endovascular cerebral revascularization
Ricky Medel1, R Webster Crowley, Aaron S Dumont
1Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA.
Endovascular cerebral revascularization is a growing alternative to surgery for atherosclerotic disease. This review examines hyperperfusion syndrome following endovascular interventions, highlighting knowledge gaps and treatment considerations.
Area of Science:
- Neurology
- Vascular Surgery
- Interventional Radiology
Background:
- Endovascular cerebral revascularization is increasingly used for atherosclerotic disease, particularly in the intracranial circulation.
- Carotid artery stenting shows comparable efficacy to carotid endarterectomy in select patients.
- Intracranial lesions pose a significant risk of recurrent stroke, driving the trend towards endovascular approaches.
Purpose of the Study:
- To review the current knowledge on hyperperfusion syndrome after endovascular cerebral revascularization.
- To focus on the unique aspects of endovascular treatments influencing hyperperfusion syndrome.
- To address the limited literature on hyperperfusion syndrome in percutaneous interventions.
Main Methods:
- Literature review focusing on endovascular cerebral revascularization.
- Analysis of studies reporting on hyperperfusion syndrome post-intervention.
- Comparison of hyperperfusion syndrome in endovascular versus surgical revascularization.
Main Results:
- Hyperperfusion syndrome is well-documented after carotid endarterectomy.
- Limited data exists on hyperperfusion syndrome incidence, pathophysiology, and management after endovascular interventions.
- Endovascular techniques may alter the course of hyperperfusion syndrome compared to surgery.
Conclusions:
- Further research is needed to understand and manage hyperperfusion syndrome after endovascular cerebral revascularization.
- Specific attributes of endovascular treatments require tailored approaches to hyperperfusion syndrome.
- Addressing hyperperfusion syndrome is crucial for optimizing outcomes in endovascular stroke prevention.
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