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Age-dependent reference intervals for measured bioavailable testosterone on the Siemens Advia Centaur:
Amanda C Zimmerman1, Kevin A Buhr, Scott A Lear
1Department of Pathology and Laboratory Medicine, St. Paul's Hospital and the University of British Columbia, Vancouver, BC, Canada.
Objectives:
To determine reference intervals for bioavailable testosterone for the Siemens Centaur analyzer and to assess the need for ethnicity-specific ranges for total testosterone and/or bioavailable testosterone in South Asians.
Design And Methods:
Testosterone was measured before and after ammonium sulphate precipitation on specimens collected from a small cohort of healthy male South Asians and Europeans.
Results:
Inter-ethnicity differences in BioT and TT were not significant. Age-specific BioT reference intervals are reported.
Conclusions:
Ethnicity-specific TT and BioT reference intervals for South Asians do not appear necessary.
