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Cycloheximide Chase Analysis of Protein Degradation in Saccharomyces cerevisiae
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Structure, function, and regulation of insulin-degrading enzyme.

Raymond E Hulse1, Luis A Ralat, Tang Wei-Jen

  • 1Committee on Neurobiology, The University of Chicago, Chicago, Illinois 60637, USA.

Vitamins and Hormones
|March 3, 2009
PubMed
Summary

Insulin-degrading enzyme (IDE) rapidly breaks down insulin. Recent studies reveal how IDE selectively degrades insulin, offering new therapeutic targets for insulin metabolism control.

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