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Related Concept Videos

Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

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Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
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Imaging Studies for Cardiovascular System V: CT01:28

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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Coronary Artery Disease II: Pathophysiology01:26

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Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
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Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

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The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
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Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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Related Experiment Video

Updated: May 2, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
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Evolving CT applications in ischemic heart disease.

Gorka Bastarrika1, U Joseph Schoepf

  • 1Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive, Charleston, SC 29401, USA.

Seminars in Thoracic and Cardiovascular Surgery
|March 3, 2009
PubMed
Summary
This summary is machine-generated.

Multidetector-row computed tomography (MDCT) now assesses cardiac function, perfusion, and viability in ischemic heart disease, expanding beyond coronary artery assessment. This review covers MDCT

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Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Medical Technology

Background:

  • Ischemic heart disease diagnosis traditionally relied on invasive methods.
  • Multidetector-row computed tomography (MDCT) has evolved significantly.
  • Cardiac CT applications have expanded beyond coronary artery assessment.

Purpose of the Study:

  • To review the role of cardiac MDCT in ischemic heart disease.
  • To discuss technological advances in MDCT for cardiac imaging.
  • To outline clinical indications and current applications of cardiac MDCT.

Main Methods:

  • Review of current literature and technological advancements in cardiac MDCT.
  • Discussion of basic concepts and clinical applications.
  • Analysis of the evolving role of MDCT in ischemic heart disease management.

Main Results:

  • MDCT is now capable of assessing cardiac function, perfusion, and viability.
  • Technological progress has broadened the scope of cardiac CT.
  • MDCT offers a comprehensive evaluation in ischemic heart disease.

Conclusions:

  • Cardiac MDCT plays an increasingly vital role in evaluating ischemic heart disease.
  • MDCT provides a non-invasive method for assessing multiple aspects of cardiac health.
  • Understanding MDCT's capabilities is crucial for its appropriate clinical use.