Related Experiment Video

Updated: Jun 25, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
09:57

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

Published on: September 20, 2024

Sensorimotor seizures of pediatric onset with unusual posteriorly oriented rolandic spikes

Yosuke Kakisaka1, Nobukazu Nakasato, Kazuhiro Haginoya

  • 1Department of Pediatrics, Tohoku University School of Medicine, Sendai, Miyagi, Japan.

Epilepsy Research
|March 3, 2009
PubMed

Insights

This study identifies a rare form of childhood epilepsy characterized by sensorimotor seizures and posteriorly oriented rolandic discharges, distinct from typical benign childhood epilepsy.

Area of Science:

  • Neurology
  • Epileptology
  • Pediatric Neurology

Background:

  • Benign childhood epilepsy with centro-temporal spikes (BECCT) typically presents with anteriorly oriented rolandic discharges.
  • This study investigates an atypical presentation of childhood-onset epilepsy featuring sensorimotor seizures and posteriorly oriented rolandic discharges.

Purpose of the Study:

  • To characterize a rare epilepsy syndrome in children with sensorimotor seizures and posteriorly oriented rolandic discharges.
  • To differentiate this epilepsy subtype from typical BECCT.

Main Methods:

  • Retrospective analysis of 7 pediatric patients (under 13 years) with sensorimotor seizures and no MRI abnormalities.
  • Simultaneous electroencephalography and magnetoencephalography (MEG) were used to detect posteriorly oriented rolandic discharges.

Main Results:

  • Patients experienced rolandic and atypical seizures (e.g., falling, head dropping, auditory hallucinations).
  • Five patients had medically intractable seizures; two had well-controlled seizures with varying outcomes.
  • Magnetoencephalography effectively detected posteriorly oriented rolandic discharges.

Conclusions:

  • Posteriorly oriented rolandic discharges, detected by MEG, are indicative of an epilepsy type that excludes BECCT.
  • This finding highlights a distinct epilepsy syndrome in children.
Abstract

More Related Videos

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale07:35

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale

Published on: July 8, 2025

Related Concept Videos

Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures ll: Types01:19

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...