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SURF imaging for contrast agent detection.

Rune Hansen¹, Bjørn A J Angelsen

¹Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control

|March 3, 2009

Summary

A novel Second Order Ultrasound Field (SURF) contrast imaging technique enhances diagnostic capabilities by processing dual frequency band pulses. This method improves ultrasound contrast agent detection, especially for bubbles above resonance frequency.

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Area of Science:

Medical Imaging
Biomedical Engineering
Acoustics

Background:

Current contrast agent detection methods in ultrasound imaging face limitations.
Improving diagnostic significance of ultrasound contrast agents is crucial for medical applications.

Purpose of the Study:

To introduce and evaluate the Second Order Ultrasound Field (SURF) contrast imaging method.
To demonstrate SURF's potential to overcome limitations of existing contrast agent detection techniques.

Main Methods:

Utilizing dual frequency band pulse complexes with overlapping high-frequency (HF) and low-frequency (LF) pulses.
Employing HF pulses for image reconstruction and LF pulses to manipulate contrast agent scattering properties.
Processing received signals to achieve SURF contrast imaging.

Main Results:

SURF contrast imaging decouples resonant properties of contrast agents from HF imaging pulses.
The technique shows promise for imaging contrast bubbles above their resonance frequency.
Initial in vitro measurements demonstrate the feasibility of the SURF method.

Conclusions:

SURF contrast imaging offers potential improvements in diagnostic significance for ultrasound contrast agents.
Correction for nonlinear effects in wave propagation is necessary for adequate specificity.
This technique is particularly valuable for advanced ultrasound imaging applications.