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Contradictory correlations between derived scales.

M J Thompson1, D J Hand, B S Everitt

  • 1Faculty of Mathematics, Open University, Milton Keynes, U.K.

Statistics in Medicine
|August 1, 1991
PubMed
Summary
This summary is machine-generated.

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Pain relief scales showed a negative correlation, but total pain scales had zero correlation. This difference is due to inverse pain relief scoring and varying pain durations among patients.

Area of Science:

  • Clinical research
  • Pain management
  • Biostatistics

Background:

  • Pain relief scales are often used in clinical trials to measure treatment efficacy.
  • Different scales may use inverse scoring, leading to negative correlations.

Purpose of the Study:

  • To explain the apparent contradiction between negatively correlated pain relief scales and uncorrelated total pain scales.
  • To investigate the impact of inverse scoring and pain duration on correlation analysis.

Main Methods:

  • Clinical trial data analysis.
  • Calculation of total pain by multiplying average pain relief by pain duration.
  • Correlation analysis of different pain measurement scales.

Main Results:

Related Experiment Videos

  • Individual pain relief scales exhibited a large negative correlation.
  • Derived total pain scales, accounting for pain duration, showed an almost zero correlation.
  • The discrepancy was attributed to the inverse relationship of the relief scales and significant patient-specific pain durations.

Conclusions:

  • The choice of measurement scale and consideration of pain duration are critical in interpreting correlation in pain research.
  • Apparent contradictions in correlation can be resolved by accounting for underlying variables like duration.