Efficacy of electroconvulsive therapy in Fahr disease associated with bipolar psychotic disorder: a case report
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Updated: Jun 25, 2026

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
Published on: August 15, 2017
Francesco Casamassima1, Lorenzo Lattanzi, Roy H Perlis
1Division of Psychiatry, University of Pisa, Pisa, Italy. fcasamassima@hotmail.it
Abstract:
We report a case of a patient with Fahr disease affected by bipolar disorder type I with psychotic symptoms. The complex clinical picture, characterized by both neurological and psychiatric symptoms, proved to be partially or completely resistant to several pharmacological trials. On the contrary, a marked improvement of clinical picture occurred after a cycle of 10 sessions of electroconvulsive therapy, followed by a complete and sustained resolution of mood, cognitive, motor, and behavioral symptoms during the next 4 years.
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