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Updated: Jun 25, 2026

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition
Published on: June 21, 2024
Interobserver reproducibility in reporting on renal cortical scintigraphy in children: a large collaborative study.
Marianne C Tondeur1, Diego De Palma, Isabel Roca
1Department of Radioisotopes, CHU St Pierre, Brussels, Belgium. Marianne_Tondeur@stpierre-bru.be
Interobserver agreement for technetium-99m dimercaptosuccinic acid (99mTc-DMSA) scans in children is good. Addressing normal variants can further improve reproducibility in pediatric nuclear medicine reporting.
Area of Science:
- Pediatric Nuclear Medicine
- Radiology Reporting
- Medical Imaging Interpretation
Background:
- Technetium-99m dimercaptosuccinic acid (99mTc-DMSA) scans are crucial for evaluating pediatric kidney conditions.
- Assessing interobserver agreement is vital for standardizing scan interpretation.
Purpose of the Study:
- To evaluate the interobserver reproducibility in the interpretation of 99mTc-DMSA scans in children.
- To identify factors contributing to disagreement among nuclear medicine physicians.
Main Methods:
- Sixty 99mTc-DMSA scans from three centers were reviewed by 61 nuclear medicine physicians globally.
- Observers classified kidney findings as normal, abnormal, equivocal, or poor quality, noting lesion location.
- Responses were collected via email.
Main Results:
- A median agreement of 93% was observed among the 61 international observers.
- Disagreement occurred in 24% of kidneys, primarily due to equivocal findings rather than normality/abnormality misclassification.
- Common causes for disagreement included normal variants, congenital anomalies, and small defects.
Conclusions:
- Interobserver reproducibility for 99mTc-DMSA scans in children is generally good across a wide range of international experts.
- Standardizing the recognition of normal variants can enhance the consistency of scan reporting in pediatric nuclear medicine.
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