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Updated: Jun 25, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
[Severe mixed prosthetic double-discs mitral valve dysfunction due to thrombosis - a case report]
Ireneusz Jedliński1, Małgorzata Duszyńska, Jan Wojna
1Oddział Kardiologiczny, Szpital im. J. Strusia, ul. Szkolna 8/12, 61-833 Poznań. irejed@wp.pl
Acute thrombosis of a mechanical mitral valve prosthesis is rare. This case highlights a patient who developed heart failure due to prosthetic valve dysfunction, requiring reoperation after failed thrombolytic therapy.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Biomedical Engineering
Background:
- Rheumatic heart disease necessitates mitral valve replacement with mechanical prostheses.
- Mechanical mitral valve prostheses, such as the St. Jude Medical device, are durable but can be subject to complications.
- Prosthetic valve dysfunction remains a significant concern in cardiac surgery patients.
Observation:
- A 58-year-old male presented with acute heart failure symptoms (NYHA class IV) three years post-mitral valve replacement.
- Transthoracic and transesophageal echocardiography revealed mixed prosthetic mitral valve dysfunction.
- Disc motion abnormalities indicative of thrombosis were identified on echocardiography.
Findings:
- The patient experienced acute thrombosis of the mechanical mitral valve prosthesis.
- Thrombolytic treatment was unsuccessful in resolving the prosthetic valve dysfunction.
- The patient required reoperation for biological mitral valve replacement.
Implications:
- This case underscores the potential for rare but serious complications like acute thrombosis with mechanical heart valves.
- Prompt diagnosis and management are crucial for patients with suspected prosthetic valve dysfunction.
- Reoperation with a biological valve may be necessary when thrombolysis fails in cases of mechanical valve thrombosis.
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