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[Human mobile genetic elements: structure, distribution and functional role].
Mobile genetic elements, comprising 45% of the human genome, are crucial for genome function. This review covers their roles in recombination, gene expression regulation, and neogene formation, alongside classification and distribution.
Area of Science:
- Genetics
- Molecular Biology
- Genomics
Context:
- Human genome comprises 45% mobile genetic elements.
- Mobile genetic elements are key players in genome evolution and function.
Purpose:
- To review data on human mobile genetic elements.
- To focus on their roles in genome functioning, including recombination, gene expression regulation, and neogene formation.
- To discuss their classification and distribution.
Summary:
- Mobile genetic elements (MGEs) constitute a significant portion of the human genome.
- Their functions encompass crucial genomic processes like recombination and gene expression regulation.
- The review details MGE classification, distribution, and involvement in creating novel genes.
Impact:
- Provides a comprehensive overview of mobile genetic elements in the human genome.
- Highlights the functional significance of MGEs in genetic regulation and evolution.
- Serves as a foundational resource for researchers studying genome dynamics and plasticity.
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