Related Experiment Videos
Moraxella catarrhalis pneumonia in an AIDS patient: a case report
Attapon Cheepsattayakorn1, Prasit Tharavichitakul, Sakchai Dettrairat
110th Zonal Tuberculosis and Chest Disease Center, Chiang Mai, 10th Office of Disease Prevention and Control, Department of Disease Control, Ministry of Public Health, Thailand. attaponche@yahoo.com
Abstract:
Moraxella catarrhalis pneumonia, although in the immunocompromised patients is very uncommon for community-acquired pneumonia (CAP). It demonstrates a potential pathogen with high mortality when the presence of heavy numbers of organisms, intracellularly and extracellularly, in the sputum Gram's stained smears confirmed by cultures. In 2007, the authors reported a case of a 28-year-old Thai single male patient with acquired-immunodeficiency syndrome (AIDS) and Moraxella catarrhalis pneumonia who dramatically responded to two weeks of oral Amoxyclav (Amoxycillin trihydrate 500 milligrams + Clavulanic acid (Potassium clavulanate) 125 milligrams) treatment at 625 milligrams every 8 hours and then discharged. The present case report describes clinical and initial chest roentgenographic presentations of Moraxella catarrhalis pneumonia in AIDS patient. The importance of chest roentgenographic pictures, CD4/CD8-T lymphocyte ratio, sputum Gram's stainings, cultures with susceptibility testing in establishing a diagnosis, and protective vaccine are discussed.
Insights
Moraxella catarrhalis pneumonia is a rare but serious infection in immunocompromised patients, particularly those with acquired immunodeficiency syndrome (AIDS). Early diagnosis through sputum analysis and imaging is crucial for effective treatment and improved outcomes.
Area of Science:
- Infectious Diseases
- Pulmonology
- Immunology
Background:
- Community-acquired pneumonia (CAP) is uncommon in immunocompromised individuals.
- Moraxella catarrhalis can be a high-mortality pathogen when present in significant numbers.
Observation:
- A case report details Moraxella catarrhalis pneumonia in an acquired immunodeficiency syndrome (AIDS) patient.
- Clinical and initial chest roentgenographic findings are presented.
- The patient responded well to Amoxyclav treatment.
Findings:
- Diagnosis relies on sputum Gram's staining, cultures with susceptibility testing, and chest imaging.
- CD4/CD8-T lymphocyte ratio is an important diagnostic indicator.
- Moraxella catarrhalis pneumonia requires prompt and accurate diagnosis.
Implications:
- Highlights the importance of considering uncommon pathogens in immunocompromised patients.
- Emphasizes the role of diagnostic tools in managing severe pneumonia.
- Suggests the need for further research into protective vaccines against Moraxella catarrhalis.
Related Concept Videos
Atypical Pneumonia
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia I: Introduction
Cryptococcal Meningitis
Amebiasis
Pneumonia III: Complications and Assessment