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Procedural sedation in children in the emergency department: a PREDICT study

Meredith Borland1, Amanda Esson, Franz Babl

  • 1Princess Margaret Hospital, Perth, Western Australia, Australia. meredith.borland@health.wa.gov.au

Insights

Pediatric emergency departments frequently use nitrous oxide, ketamine, and midazolam for procedural sedation. However, guidelines, documentation, and staff training require improvement for better patient care.

Area of Science:

  • Pediatric Emergency Medicine
  • Clinical Practice Guidelines
  • Procedural Sedation

Background:

  • Procedural sedation is common in pediatric emergency departments.
  • Current practices and adherence to clinical practice guidelines (CPG) for procedural sedation are not well-defined across research networks.

Purpose of the Study:

  • To investigate current procedural sedation practices in the Paediatric Research in Emergency Departments International Collaborative (PREDICT) network.
  • To compare existing clinical practice guidelines (CPG) with current procedural sedation practices.
  • To identify areas for improvement and establish baseline data for future multicenter studies.

Main Methods:

  • A questionnaire was distributed to specialist emergency physicians within the PREDICT network.
  • The survey collected data on physician demographics, general procedural sedation practices, and specific sedation agents used in children.
  • Clinical practice guidelines (CPG) for general sedation and specific agents were obtained from each participating site.

Main Results:

  • Nitrous oxide (N2O), ketamine, and midazolam were the most frequently used agents for procedural sedation.
  • Formal sedation records and checklists were utilized by 57% of respondents, while 41% reported auditing sedation practices.
  • Nine sites had general sedation CPGs, but no site had a guideline for propofol administration.

Conclusions:

  • Procedural sedation in the PREDICT network commonly involves N2O, ketamine, and midazolam for diverse procedures.
  • Significant areas for improvement include the development of guidelines for specific agents, enhanced documentation, staff competency training, and auditing.
  • Further multicenter research is needed to address gaps in age cut-offs, fasting times, and optimal agent indications.
Abstract