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Isoniazid completion rates for latent tuberculosis infection among college students managed by a community pharmacist
Karl Hess1, Jeffery Goad, Joanne Wu
1College of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA. khess@westernu.edu
Objective:
The authors' objective was to document 9-month and previously recommended 6-month treatment completion rates for latent tuberculosis infection (LTBI) in a pharmacist-managed LTBI clinic in a community pharmacy on a college campus, and to describe patient characteristics.
Participants:
Participants were university students diagnosed with LTBI.
Methods:
The authors conducted a retrospective review of pharmacy records from 2000 to 2006. Main outcome measures included 6-month and 9-month LTBI treatment completion rates, total isoniazid (INH) tablets taken, characteristics of completers versus noncompleters, average time to treatment completion, and reported adverse drug events.
Results:
The 9-month completion rate was 59%, and the 6-month completion rate was 67%. Among those not completing treatment, 15.2% experienced fatigue and 2.2% experienced a rash (p=.04 and p=.03, respectively).
Conclusion:
LTBI clinics are a unique niche for community pharmacies and can provide individualized patient care to ensure LTBI treatment adherence, monitoring for disease progression, and safety of INH.
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