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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Blood Typing01:10

Blood Typing

Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...

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Related Experiment Video

Updated: Jun 25, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

Twin-twin transfusion syndrome.

A C Rossi1, V D'addario

  • 1IV Clinic of Obstetrics and Gynecology, University of Bari, Bari, Italy. acristinarossi@yahoo.it

Minerva Ginecologica
|March 4, 2009
PubMed
Summary

Twin-twin transfusion syndrome (TTTS) is a placental vascular disorder in monochorionic pregnancies. Selective laser photocoagulation of placental vessels (SLPCV) shows efficacy in treating TTTS, with a new staging system proposed.

Area of Science:

  • Perinatology
  • Maternal-Fetal Medicine
  • Fetal Surgery

Background:

  • Twin-twin transfusion syndrome (TTTS) is a serious complication unique to monochorionic pregnancies.
  • It arises from abnormal placental vascular connections (anastomoses) leading to unequal blood flow between twins.
  • Diagnosis involves ultrasound detection of amniotic fluid imbalances (oligohydramnios and polyhydramnios).

Purpose of the Study:

  • To review the effects of selective laser photocoagulation of placental vessels (SLPCV) on fetal growth and circulation in TTTS.
  • To explore prognostic factors associated with TTTS.
  • To discuss the limitations of the Quintero staging system and propose a new staging system (Rossi staging system).

Main Methods:

  • Literature review focusing on SLPCV efficacy in TTTS treatment.

More Related Videos

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
09:52

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

Published on: September 5, 2011

Related Experiment Videos

Last Updated: Jun 25, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
09:52

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

Published on: September 5, 2011

  • Analysis of studies on prognostic factors in TTTS.
  • Critical evaluation of current TTTS staging systems and proposal of a new system.
  • Main Results:

    • Growing evidence supports SLPCV as a highly efficacious therapy for TTTS compared to amnioreduction.
    • The review details the impact of SLPCV on fetal growth and circulation.
    • A new staging system, the Rossi staging system, is proposed for assessing TTTS severity.

    Conclusions:

    • SLPCV is an effective treatment for TTTS, demonstrating superior outcomes.
    • Further research is needed to clarify the natural history of TTTS and refine prognostic factors.
    • The proposed Rossi staging system aims to improve TTTS severity assessment at presentation.