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Related Experiment Video

Updated: Jun 25, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

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Modified Wise-pattern reduction mammaplasty, a new tool for upper quadrantectomies: a preliminary report.

F Santanelli1, G Paolini, A Campanale

  • 1Plastic Surgery Unit, Sant'Andrea Hospital, II School of Medicine, University of Rome La Sapienza, Rome, Italy. fabio.santanelli@uniroma1.it

Annals of Surgical Oncology
|March 4, 2009
PubMed
Summary

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Modified Wise-pattern breast reduction offers better aesthetic outcomes for early breast cancer patients undergoing quadrantectomy. This technique preserves oncological safety while improving breast shape and symmetry.

Area of Science:

  • Oncoplastic surgery
  • Breast cancer surgery
  • Plastic and reconstructive surgery

Background:

  • Quadrantectomy for early breast cancer can lead to poor aesthetic results, like breast deformity, especially with upper pole tumors.
  • Patients with moderate to severe breast hypertrophy and upper quadrant tumors are candidates for improved surgical techniques.

Purpose of the Study:

  • To evaluate a modified Wise-pattern breast reduction technique for immediate breast reconstruction after upper quadrantectomy.
  • To assess the oncological safety and aesthetic outcomes of this modified approach.

Main Methods:

  • Eleven patients with early breast cancer (cup sizes C-E) underwent upper quadrantectomy with immediate breast reconstruction using a modified Wise-pattern reduction mammaplasty.
  • Contralateral breast reduction was performed for symmetry, preserving lower pole skin to replace excised upper quadrant tissue.

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Main Results:

  • All patients achieved excellent healing within 15 days, with no local or distant recurrences observed over a mean follow-up of 26.5 months.
  • The procedure resulted in natural breast shape, with scars comparable to standard reduction mammaplasty.
  • Upper quadrant scars did not negatively impact the décolleté aesthetics.

Conclusions:

  • Modified Wise-pattern reduction mammaplasty is a safe and effective technique for immediate breast reconstruction following upper quadrantectomies.
  • This method provides superior aesthetic results, creating a natural breast mound in patients with medium to large breasts.