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Updated: Jun 25, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
09:57

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit

Published on: July 13, 2019

[Management of central venous catheter: prevention of thrombosis and bacteremia]

C Lomonte1, C Basile

  • 1Unita' Operativa Complessa di Nefrologia e Dialisi, Ente Ecclesiastico, Ospedale Generale Regionale F. Miulli, Acquaviva delle Fonti (Bari), Italy.

Giornale Italiano Di Nefrologia : Organo Ufficiale Della Societa Italiana Di Nefrologia
|March 4, 2009
PubMed

Insights

Central venous catheters (CVC) are vital for dialysis but prone to thrombosis and infection. Preventing CVC infections through reinforced protocols and patient involvement is key to patient safety and effective hemodialysis.

Area of Science:

  • Nephrology and Vascular Access Management
  • Infectious Diseases and Antimicrobial Stewardship

Context:

  • Increasing use of central venous catheters (CVC) in aging dialysis patients with severe comorbidities.
  • Central venous catheters are essential for hemodialysis vascular access.
  • Thrombosis and infection are primary limitations to long-term CVC use.

Purpose:

  • To review the challenges of long-term central venous catheter use in hemodialysis.
  • To discuss strategies for managing and preventing CVC-related thrombosis and infection.
  • To highlight the importance of infection control and patient involvement.

Summary:

  • Thrombosis is manageable with thrombolytics and anticoagulants.
  • Central venous catheter infections are a major cause of morbidity/mortality, requiring rapid antibiotic treatment.
  • Antibiotic lock therapy shows promise, but robust infection control procedures and patient engagement are paramount for preventing CVC-related bacteremia.

Impact:

  • Emphasizes the critical need for stringent infection control protocols in hemodialysis.
  • Highlights the role of patient education and staff training in reducing CVC complications.
  • Informs clinical practice regarding the timely management of CVC-related thrombosis and infections.

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