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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Skin Diseases and Disorders

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Staphylococcal Skin Infections

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Renewal of Skin Epidermal Stem Cells

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Cells of the Epidermis

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Related Experiment Video

Updated: Jun 25, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Cutaneous squamous cell carcinoma.

Jorge Garcia-Zuazaga¹, Suzanne M Olbricht

¹Department of Dermatology, Mohs Micrographic Surgery and Cutaneous Oncology, Lahey Clinic, Harvard Medical School, 41 Mall Road, Burlington, MA 01805, USA.

Advances in Dermatology

|March 5, 2009

Summary

This summary is machine-generated.

Cutaneous squamous cell carcinoma (SCC) is a common skin cancer primarily caused by UV radiation. Early detection and sun protection are crucial for managing this potentially life-threatening neoplasm.

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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

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Published on: August 9, 2024

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Last Updated: Jun 25, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

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Published on: August 18, 2022

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Area of Science:

Dermatology
Oncology

Background:

Cutaneous squamous cell carcinoma (SCC) is the second most common skin cancer in white populations.
UV radiation from chronic sun exposure is the primary cause, affecting sun-exposed areas like the head and neck.
Other risk factors include HPV infection, occupational exposures, genodermatoses, scarring, chronic wounds, and burn scars.

Purpose of the Study:

To review the risk factors, clinical presentation, and management of cutaneous SCC.
To highlight the increased risk in allogeneic transplant recipients and emphasize standard care protocols.
To discuss the prognosis and potential future roles of techniques like sentinel lymph node biopsy (SLNB).

Main Methods:

Review of existing literature on cutaneous SCC.
Analysis of risk factors, including UV exposure and other associated conditions.
Discussion of diagnostic and prognostic indicators, including total-body skin examination and potential for SLNB.

Main Results:

Most primary cutaneous SCC cases have an excellent prognosis with straightforward treatment.
A minority of SCCs may recur or metastasize, necessitating careful history taking and examination for high-risk tumors.
Prognosis for metastatic disease is guarded, and SLNB requires further research for routine use.

Conclusions:

Sun avoidance and protection from childhood are vital for minimizing SCC risk.
Aggressive patient education, immunosuppression control, and surveillance are crucial for transplant recipients.
Accurate diagnosis and risk stratification aid in effective management and improved patient outcomes.