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Quantification, Viability Assessment, and Visualization Strategies for Acinetobacter Biofilms
07:41

Quantification, Viability Assessment, and Visualization Strategies for Acinetobacter Biofilms

Published on: August 4, 2023

[Bacteremia caused by Acinetobacter baumannii among patients in critical care]

Guadalupe Aguirre-Avalos1, Julio César Mijangos-Méndez, Martha Luz Zavala-Silva

  • 1Servicio de Terapia Intensiva, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, México. gaguirre@cencar.udg.mx

Gaceta Medica De Mexico
|March 5, 2009
PubMed
Abstract

Insights

Acinetobacter baumannii blood infections (AbBI) are common in ICUs, often leading to severe sepsis and septic shock. These infections significantly increase patient mortality rates.

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Microbiology

Background:

  • Acinetobacter baumannii blood infections (AbBI) pose a significant threat in Intensive Care Units (ICUs).
  • Understanding the epidemiology and clinical course of AbBI is crucial for effective patient management.

Purpose of the Study:

  • To determine the severity and clinical course of Acinetobacter baumannii blood infections (AbBI).
  • To analyze the incidence, acquisition patterns, and mortality associated with AbBI in an ICU setting.

Main Methods:

  • Prospective review of all Acinetobacter baumannii isolates from an ICU.
  • Identification of patients with AbBI and analysis of their clinical data.
  • Assessment of infection acquisition time, clinical presentation, and mortality rates.

Main Results:

  • 46 patients had AbBI, with an incidence of 14 per 1,000 admissions; 85% were ICU-acquired.
  • Common presentations included septic shock (42%) and severe sepsis (42%); 17% of isolates were imipenem-resistant.
  • Mortality was high: 45% for AbBI alone, 40% for polymicrobial BI, and 60% for septic shock.

Conclusions:

  • AbBI demonstrated an endemic pattern in the studied ICU.
  • Severe sepsis and septic shock were the predominant clinical manifestations of AbBI.
  • AbBI significantly increased the mortality rate among ICU patients.

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