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Updated: Jun 25, 2026

Long-term High-Resolution Intravital Microscopy in the Lung with a Vacuum Stabilized Imaging Window
Published on: October 6, 2016
A versatile and reliably reusable ultrahigh vacuum viewport
K J Weatherill1, J D Pritchard, P F Griffin
1Department of Physics, Durham University, Durham DH1 3LE, United Kingdom. k.j.weatherill@durham.ac.uk
Abstract:
We present a viewport for use in ultrahigh vacuum (UHV) based upon the preflattened solder seal design presented in earlier work [Cox et al., Rev. Sci. Instrum. 74, 3185 (2003)]. The design features significant modifications to improve long term performance. The windows have been leak tested to less than 10(-10) atm cm(3)/s. From atom number measurements in an optical dipole trap loaded from a vapor cell magneto-optical trap inside a vacuum chamber accommodating these viewports, we measure a trap lifetime of 9.5 s suggesting a pressure of around 10(-10) Torr limited by background rubidium vapor pressure. We also present a simplified design where the UHV seal is made directly to a vacuum pipe.

