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Updated: Jun 25, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Three-dimensional analysis in facial asymmetry: comparison with model analysis and conventional two-dimensional
Alessandro Moro1, Pasquale Correra, Roberto Boniello
1Department of Maxillofacial Surgery, Catholic University, Rome, Italy.
Computed tomographic (CT) three-dimensional analysis offers superior anatomical detail compared to model analysis for diagnosing occlusal plane tilting in facial asymmetry. This advanced CT imaging aids in identifying individual anatomical variations, crucial for severe craniofacial asymmetry cases.
Area of Science:
- Dentistry
- Medical Imaging
- Orthodontics
Background:
- Facial asymmetry presents diagnostic challenges in evaluating occlusal plane tilting.
- Accurate assessment of occlusal plane tilting is crucial for effective treatment planning in orthodontics and craniofacial surgery.
Purpose of the Study:
- To compare computed tomographic (CT) three-dimensional analysis with traditional model analysis as a diagnostic aid for occlusal plane tilting in patients with facial asymmetry.
- To evaluate the utility of CT three-dimensional analysis in identifying individual anatomical variations.
Main Methods:
- Ten patients with facial asymmetry underwent three-dimensional CT scans, plaster cast analysis, and two-dimensional cephalometric analysis.
- Measurements of occlusal plane tilting were taken using three-dimensional CT, plaster models (on an articulator), and cephalograms.
- Quantitative data from each method were compared to assess concordance and identify discrepancies.
Main Results:
- Quantitative measurements of occlusal tilting were similar across all three methods.
- Three-dimensional CT provided a more comprehensive representation of individual anatomy, reducing interpretative challenges.
- CT analysis proved effective in detecting specific anatomical variations relevant to occlusal plane tilting.
Conclusions:
- Three-dimensional CT analysis is a valuable tool for diagnosing occlusal plane tilting in facial asymmetry.
- Its ability to accurately depict individual anatomical variations makes it particularly useful for complex craniofacial cases.
- CT three-dimensional analysis can enhance diagnostic accuracy and aid in treatment planning for severe craniofacial asymmetry.
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