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Updated: Jun 25, 2026

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
Published on: September 22, 2017
Cellular resolution volumetric in vivo retinal imaging with adaptive optics-optical coherence tomography
Robert J Zawadzki1, Stacey S Choi, Alfred R Fuller
1Vision Science and Advanced Retinal Imaging Laboratory (VSRI), Department of Ophthalmology & Vision Science,University of California Davis, 4860 Y Street, Suite 2400, Sacramento, California 95817, USA. rjzawadzki@ucdavis.edu
Abstract:
Ultrahigh-resolution adaptive optics-optical coherence tomography (UHR-AO-OCT) instrumentation allowing monochromatic and chromatic aberration correction was used for volumetric in vivo retinal imaging of various retinal structures including the macula and optic nerve head (ONH). Novel visualization methods that simplify AO-OCT data viewing are presented, and include co-registration of AO-OCT volumes with fundus photography and stitching of multiple AO-OCT sub-volumes to create a large field of view (FOV) high-resolution volume. Additionally, we explored the utility of Interactive Science Publishing by linking all presented AO-OCT datasets with the OSA ISP software.

