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Medical sonography: reproductive effects and risks.
R L Brent1, R P Jensh, D A Beckman
1Department of Pediatrics, Thomas Jefferson University, Jefferson Medical College, Philadelphia, Pennsylvania.
Teratology
|August 1, 1991
Summary
Diagnostic ultrasound (sonography) is generally safe for developing fetuses. Prudent use and equipment design are key to maintaining exposures below harmful levels, especially considering potential risks from elevated temperatures.
Area of Science:
- Medical Imaging and Diagnostics
- Reproductive Health
- Biophysics
Background:
- Medical sonography, or ultrasound, is a widely used diagnostic imaging technique.
- While generally considered safe, concerns exist regarding potential reproductive and teratogenic risks with elevated ultrasound exposure.
- Understanding dose-response relationships and biological plausibility is crucial for assessing safety.
Purpose of the Study:
- To evaluate the reproductive risks associated with diagnostic ultrasound exposure.
- To determine safe exposure limits for medical sonography, particularly during pregnancy.
- To provide recommendations for prudent use and equipment design.
Main Methods:
- Evaluation of reproductive risks using five criteria: human epidemiology, secular trend data, animal experiments, dose-response relationships, and biological plausibility.
- Analysis of existing human epidemiological data regarding diagnostic ultrasound and fetal development.
- Review of animal studies investigating the effects of ultrasound on embryonic and fetal development, focusing on temperature elevation.
Main Results:
- Human epidemiological data does not indicate measurable risks to the developing embryo or fetus from diagnostic ultrasound.
- Animal studies show that diagnostic ultrasound levels are safe and do not cause harmful fetal temperature increases.
- Elevated ultrasound exposure can increase embryonic temperature, highlighting the need for caution in pregnant patients, especially if febrile.
Conclusions:
- Diagnostic ultrasound is considered safe when exposures are maintained below levels that could cause significant temperature elevation (e.g., exceeding 39°C).
- Prudent use by clinicians and thoughtful equipment design are essential to minimize any hypothetical risks.
- The terms 'sonography' and 'sonogram' are recommended for clarity and reduced patient anxiety.