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[Changes in MR images in pre-eclampsia and eclampsia]
L Hellmeyer1, J Iwinska-Zelder, L Gerken
1Kinik für Geburtshilfe und Perinatalmedizin, Philipps-Universität Marburg. hellmeye@med.uni-marburg.de
Zeitschrift Fur Geburtshilfe Und Neonatologie
|March 5, 2009
Summary
Neurological symptoms in pre-eclampsia, like seizures and blindness, correlate with brain imaging findings. These reversible white matter lesions, classified as posterior reversible encephalopathy syndrome (PRES), resolve with treatment.
Area of Science:
- Neurology
- Radiology
- Obstetrics
Background:
- Pre-eclampsia is a serious pregnancy complication affecting 2% of pregnancies.
- It is a leading cause of maternal and infant mortality and morbidity.
- Neurological symptoms include headache, seizures, and visual disturbances.
Observation:
- This study investigated the correlation between neurological symptoms and MRI findings in pre-eclampsia.
- MRI revealed white matter hyperintensities in the occipital region and basal ganglia in patients with eclamptic seizures and blindness.
- These neurological and radiological abnormalities resolved within 3-5 days.
Findings:
- Cerebral lesions observed in pre-eclampsia can be classified as posterior reversible encephalopathy syndrome (PRES) or reversible leukoencephalopathy syndrome (PLES).
- MRI findings directly correlate with the neurological manifestations of pre-eclampsia.
Implications:
- MRI aids in differentiating pre-eclampsia-related neurological conditions from non-pregnancy-related cerebral diseases.
- Imaging findings support therapeutic planning for pre-eclampsia patients.
- Early diagnosis and management of PRES/PLES can improve maternal and fetal outcomes.
