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[Changes in MR images in pre-eclampsia and eclampsia].

L Hellmeyer1, J Iwinska-Zelder, L Gerken

  • 1Kinik für Geburtshilfe und Perinatalmedizin, Philipps-Universität Marburg. hellmeye@med.uni-marburg.de

Zeitschrift Fur Geburtshilfe Und Neonatologie
|March 5, 2009
PubMed
Summary

Neurological symptoms in pre-eclampsia, like seizures and blindness, correlate with brain imaging findings. These reversible white matter lesions, classified as posterior reversible encephalopathy syndrome (PRES), resolve with treatment.

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Area of Science:

  • Neurology
  • Radiology
  • Obstetrics

Background:

  • Pre-eclampsia is a serious pregnancy complication affecting 2% of pregnancies.
  • It is a leading cause of maternal and infant mortality and morbidity.
  • Neurological symptoms include headache, seizures, and visual disturbances.

Observation:

  • This study investigated the correlation between neurological symptoms and MRI findings in pre-eclampsia.
  • MRI revealed white matter hyperintensities in the occipital region and basal ganglia in patients with eclamptic seizures and blindness.
  • These neurological and radiological abnormalities resolved within 3-5 days.

Findings:

  • Cerebral lesions observed in pre-eclampsia can be classified as posterior reversible encephalopathy syndrome (PRES) or reversible leukoencephalopathy syndrome (PLES).

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  • MRI findings directly correlate with the neurological manifestations of pre-eclampsia.

    • Implications:

    • MRI aids in differentiating pre-eclampsia-related neurological conditions from non-pregnancy-related cerebral diseases.
    • Imaging findings support therapeutic planning for pre-eclampsia patients.
    • Early diagnosis and management of PRES/PLES can improve maternal and fetal outcomes.