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[Changes in MR images in pre-eclampsia and eclampsia]
L Hellmeyer1, J Iwinska-Zelder, L Gerken
1Kinik für Geburtshilfe und Perinatalmedizin, Philipps-Universität Marburg. hellmeye@med.uni-marburg.de
Background:
Pre-eclampsia affects 2% of pregnancies. This multisystem disorder is a major cause of maternal, foetal and neonatal mortality and morbidity. Neurological manifestations of eclampsia are headache, nausea, vomiting, cortical blindness and recurrent seizures.
Objective:
The purpose of this study was to determine whether the neurological symptoms correlate with MR imaging findings.
Results:
In a patient with eclamptic seizure and another one with blindness due to pre-eclampsia, the white matter hyperintensities on T (2)-weighted MR and FLAIRsequence images could be demonstrated in the occipital region and in the basal ganglia. Within 3-5 days all neurological symptoms and radiological abnormalities had resolved.
Conclusion:
These cerebral lesions could be classified as posterior reversible encephalopathy syndrome (PRES) or as reversible leukoencephalopathy syndrome (PLES). Thus, MRI supports differential diagnosis regarding non pregnancy-related cerebral disease and can be helpful for therapy planning in cases of pre-eclampsia.
