Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prothrombin Himi; an abnormal prothrombin characterized by a defective thrombin activity.

E Morishita1, M Saito, H Asakura

  • 1Department of Internal Medicine (III), Kanazawa University School of Medicine, Japan.

Thrombosis Research
|June 15, 1991
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A case of acquired FXIII deficiency with severe bleeding symptoms.

Haemophilia : the official journal of the World Federation of Hemophilia·2012
Same author

Haemostatic management of surgery for imperforate anus in a patient with 13q deletion syndrome with combined deficiency of factors VII and X.

Haemophilia : the official journal of the World Federation of Hemophilia·2008
Same author

Selective inducible nitric oxide synthase inhibition attenuates organ dysfunction and elevated endothelin levels in LPS-induced DIC model rats.

Journal of thrombosis and haemostasis : JTH·2005
Same author

Beneficial effect of JTV-803, a new synthetic inhibitor of activated factor X, against both lipopolysaccharide-induced and tissue factor-induced disseminated intravascular coagulation in rat models.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis·2002
Same author

Vitamin K administration to elderly patients with osteoporosis induces no hemostatic activation, even in those with suspected vitamin K deficiency.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2002
Same author

Decreased plasma activity of antithrombin or protein C is not due to consumption coagulopathy in septic patients with disseminated intravascular coagulation.

European journal of haematology·2001

A novel abnormal prothrombin, "Prothrombin Himi," was identified in a patient with normal antigen levels but significantly reduced activity. This indicates a defect in thrombin enzymatic activity, impacting blood clotting.

Area of Science:

  • Biochemistry
  • Hematology
  • Molecular Biology

Background:

  • Prothrombin is a crucial protein in the blood coagulation cascade.
  • Defects in prothrombin can lead to bleeding disorders or thrombotic events.
  • Understanding abnormal prothrombin variants is essential for diagnosing and managing coagulation disorders.

Related Experiment Videos