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Contraindication of angiotensin-converting enzyme (ACE) inhibitors for patients receiving therapeutic plasma
1Medical University of South Carolina, Charleston, SC, USA.
Therapeutic plasma exchange is a therapy in which the plasma portion of the blood is removed by a device known as a cell separator. The separator works by spinning the blood at high speed to separate the cells from the fluid and returning the remaining cells to the patient, while the plasma is discarded and substituted with replacement fluids. Common complications of plasma exchange include the occurrence of hypotensive reactions. This article reviews the current literature in an attempt to clarify the correlation between the use of angiotensin-converting enzyme (ACE) inhibitors and hypotensive patient reactions, as well as examines the need for policy and guideline development regarding the combined therapies, and finishes by further examining future research implications.
Therapeutic plasma exchange is a therapy in which the plasma portion of the blood is removed by a device known as a cell separator. The separator works by spinning the blood at high speed to separate the cells from the fluid and returning the remaining cells to the patient, while the plasma is discarded and substituted with replacement fluids. Common complications of plasma exchange include the occurrence of hypotensive reactions. This article reviews the current literature in an attempt to clarify the correlation between the use of angiotensin-converting enzyme (ACE) inhibitors and hypotensive patient reactions, as well as examines the need for policy and guideline development regarding the combined therapies, and finishes by further examining future research implications.
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