Related Experiment Video
Updated: Jun 25, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
An extremely rare case of large Delphian node metastasis preceding primary laryngeal cancer
Shigeyuki Murono1, Kyoko Hirota, Satoru Kondo
1Department of Otolaryngology, Head and Neck Surgery, Kanazawa University, Takaramachi, Japan. murono@med.kanazawa-u.ac.jp
Objectives:
To present an extremely rare case of large Delphian node metastasis preceding primary laryngeal cancer.
Materials And Methods:
A 74-year-old male who noted a mass on the lower anterior neck and consulted our department immediately. The mass rapidly grew to 6cm from 2cm in diameter within 2 months after the initial presentation.
Results:
Fiberoptic laryngoscopy was unremarkable. Surgical excision of the lesion showed well differentiated squamous cell carcinoma with invasion into the surrounding tissues. Postoperative radiotherapy was added. During follow-up after those treatments, thickening of the right vocal cord was observed, which gradually became more apparent. Total laryngectomy was performed 13 months after the initial operation.
Conclusion:
Delphian node metastasis is included in the differential diagnosis in a case of rapidly increasing mass in the anterior neck.
