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Updated: Jun 25, 2026

Ear Plaster Therapy as a Safe and Effective Treatment for Gestational Vomiting

Ear Plaster Therapy as a Safe and Effective Treatment for Gestational Vomiting

Published on: August 4, 2023

Management strategies for hyperemesis.

Cecilia Bottomley¹, Tom Bourne

¹Department of Obstetrics and Gynaecology, St George's University of London, Cranmer Terrace, London, UK. ceciliabottomley@doctors.org.uk

Best Practice & Research. Clinical Obstetrics & Gynaecology

|March 6, 2009

Summary

Hyperemesis gravidarum, a severe pregnancy complication, requires supportive care including rehydration and antiemetics. This review covers its diagnosis, management, and serious complications like Wernicke encephalopathy.

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Published on: June 21, 2024

Area of Science:

Obstetrics and Gynecology
Maternal-Fetal Medicine

Background:

Nausea and vomiting affect up to 80% of pregnancies.
Hyperemesis gravidarum (HG) is a severe form, impacting up to 1.5% of pregnancies, leading to dehydration and ketonuria.
HG can be disabling and life-threatening if untreated.

Purpose of the Study:

To review the diagnosis and management of hyperemesis gravidarum.
To discuss the prevention, recognition, and treatment of serious HG complications.
To evaluate current therapeutic options for HG.

Main Methods:

Literature review of existing studies and clinical guidelines.
Synthesis of evidence regarding the safety and efficacy of antiemetic treatments.
Discussion of potential complications and their management.

Main Results:

Antihistamines, phenothiazines, and metoclopramide have good safety data for HG treatment.
Efficacy trials for antiemetics in HG are lacking, with limited evidence for optimal therapy selection.
Serious complications include Wernicke encephalopathy, osmotic demyelination syndrome, and thromboembolism.

Conclusions:

Hyperemesis gravidarum necessitates prompt supportive care, including rehydration and nutritional support.
While several antiemetics are considered safe, evidence for optimal efficacy is limited.
Vigilance for and prompt treatment of severe complications are crucial for maternal and fetal well-being.