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Renal transplant: nonenhanced renal MR angiography with magnetization-prepared steady-state free precession

Xin Liu1, Natasha Berg, John Sheehan

  • 1Department of Radiology, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611, USA. xin.liu@sub.siat.ac.cn

Radiology
|March 6, 2009
PubMed

Insights

Nonenhanced magnetic resonance (MR) angiography using steady-state free precession (SSFP) with inversion recovery shows comparable image quality and renal artery stenosis detection to contrast-enhanced MR angiography in renal transplant recipients.

Area of Science:

  • Radiology
  • Medical Imaging
  • Nephrology

Background:

  • Renal artery stenosis is a common complication in renal transplant recipients.
  • Contrast-enhanced magnetic resonance (MR) angiography is a standard imaging technique, but concerns exist regarding nephrotoxicity.
  • Nonenhanced MR angiography techniques are being explored as safer alternatives.

Purpose of the Study:

  • To evaluate the efficacy of nonenhanced MR angiography with steady-state free precession (SSFP) and inversion recovery for assessing renal arteries in renal transplant patients.
  • To compare the diagnostic performance and image quality of nonenhanced SSFP MR angiography with contrast-enhanced MR angiography.

Main Methods:

  • A prospective study involving thirteen renal transplant recipients.
  • All participants underwent nonenhanced SSFP MR angiography followed by contrast-enhanced MR angiography.
  • Image quality and the presence of renal artery stenosis were assessed and compared between the two techniques.

Main Results:

  • Nonenhanced SSFP MR angiography successfully identified three cases of renal artery stenosis (two mild, one severe).
  • Findings from nonenhanced SSFP MR angiography were in agreement with contrast-enhanced MR angiography.
  • No significant difference in image quality was observed between the nonenhanced and contrast-enhanced methods.

Conclusions:

  • Nonenhanced SSFP MR angiography with inversion recovery provides comparable image quality for evaluating renal transplant arteries.
  • This nonenhanced technique is effective in detecting renal artery stenosis in renal transplant recipients.
  • Nonenhanced SSFP MR angiography represents a viable alternative to contrast-enhanced techniques, potentially reducing risks associated with contrast agents.

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