Related Experiment Video
Updated: Jun 25, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Coronary artery disease among hypertensive patients undergoing coronary computed tomography angiography
Abdel-Rauf Zeina1, Elisha Barmeir, Ghassan Zaid
1Department of Radiology and MAR Imaging Institute, Israel. raufzeina3@hotmail.com
Insights
Hypertension significantly increases the prevalence and severity of coronary artery disease (CAD). Longer hypertension duration correlates with more extensive CAD, highlighting the need for early detection in hypertensive individuals.
Area of Science:
- Cardiology
- Hypertension Research
- Diagnostic Imaging
Background:
- Coronary artery disease (CAD) is a major cause of death in hypertensive patients.
- The exact prevalence of CAD in this population remains unclear.
- Hypertension is a significant risk factor for cardiovascular disease.
Purpose of the Study:
- To determine the prevalence and severity of CAD in hypertensive patients.
- To investigate the relationship between hypertension duration and CAD.
- To assess the utility of coronary computed tomography angiography (CCTA) in evaluating CAD in hypertensive patients.
Main Methods:
- A cohort of 352 patients undergoing CCTA was analyzed.
- Patients were divided into hypertensive (n=125) and normotensive (n=227) groups.
- CAD was defined as coronary atherosclerosis; findings were compared between groups.
Main Results:
- CAD was more prevalent in hypertensive patients (82%) compared to normotensive patients (72%) (P < 0.0001).
- Hypertensive patients exhibited twice the rate of obstructive CAD and more plaques per segment.
- Hypertension duration of ≥10 years was associated with increased CAD in coronary segments.
Conclusions:
- Hypertension is linked to a higher prevalence and greater severity of CAD.
- CAD severity escalates with the duration of hypertension.
- CCTA can aid in identifying high-risk hypertensive patients for further ischemia evaluation.
Objective:
Coronary artery disease (CAD) is a leading cause of morbidity and mortality in hypertensive patients. However, the true prevalence of CAD in hypertensive patients is unknown. The aim of our study was to investigate the relationship between CAD and hypertension in patients undergoing coronary computed tomography (CT) angiography (CCTA).
Methods:
Three hundred and fifty-two consecutive patients were referred for cardiac evaluation, 125 with hypertension and 227 without hypertension. There were no statistical differences between the groups in several parameters: age, sex, and CAD risk factors. CAD was defined as coronary atherosclerosis, with obstructive or nonobstructive lesions. CCTA was performed, and findings were compared between patients with hypertension and those without.
Results:
CAD was present in 103 (82%) hypertensive and 164 (72%) normotensive patients (P < 0.0001). Obstructive CAD was twice as common in hypertensive patients, and they had more plaques per coronary segment than did normotensive patients. Patients with hypertension duration of at least 10 years had more segments with CAD.
Conclusion:
CAD is more prevalent and severe in hypertensive patients than in normotensive patients. CAD severity increases with hypertension duration. CCTA may help to identify high-risk patients needing further evaluation for subclinical ischemia.
Related Concept Videos
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Acute Coronary Syndrome III: Diagnostic Studies
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
