Coronary artery disease among hypertensive patients undergoing coronary computed tomography angiography

Abdel-Rauf Zeina1, Elisha Barmeir, Ghassan Zaid

  • 1Department of Radiology and MAR Imaging Institute, Israel. raufzeina3@hotmail.com

Insights

Hypertension significantly increases the prevalence and severity of coronary artery disease (CAD). Longer hypertension duration correlates with more extensive CAD, highlighting the need for early detection in hypertensive individuals.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Diagnostic Imaging

Background:

  • Coronary artery disease (CAD) is a major cause of death in hypertensive patients.
  • The exact prevalence of CAD in this population remains unclear.
  • Hypertension is a significant risk factor for cardiovascular disease.

Purpose of the Study:

  • To determine the prevalence and severity of CAD in hypertensive patients.
  • To investigate the relationship between hypertension duration and CAD.
  • To assess the utility of coronary computed tomography angiography (CCTA) in evaluating CAD in hypertensive patients.

Main Methods:

  • A cohort of 352 patients undergoing CCTA was analyzed.
  • Patients were divided into hypertensive (n=125) and normotensive (n=227) groups.
  • CAD was defined as coronary atherosclerosis; findings were compared between groups.

Main Results:

  • CAD was more prevalent in hypertensive patients (82%) compared to normotensive patients (72%) (P < 0.0001).
  • Hypertensive patients exhibited twice the rate of obstructive CAD and more plaques per segment.
  • Hypertension duration of ≥10 years was associated with increased CAD in coronary segments.

Conclusions:

  • Hypertension is linked to a higher prevalence and greater severity of CAD.
  • CAD severity escalates with the duration of hypertension.
  • CCTA can aid in identifying high-risk hypertensive patients for further ischemia evaluation.
Abstract

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