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Updated: Jun 25, 2026

Measurement of Myocardial Lactate Production for Diagnosis of Coronary Microvascular Spasm
Published on: September 17, 2021
Catheter-induced left main coronary artery spasm
Neeraj Parakh1, Sandeep Singh, Ravi S Math
1All India Institute of Medical Sciences, New Delhi, India.
Catheterization can cause left main coronary artery spasm, a serious condition. Prompt diagnosis and nitroglycerin treatment successfully resolved the spasm, preventing unnecessary bypass surgery.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Medicine
Background:
- Coronary artery spasm is a potential complication during cardiac catheterization procedures.
- Left main coronary artery spasm can lead to severe ischemic events.
- Accurate diagnosis is crucial to guide appropriate management and avoid invasive interventions.
Observation:
- A case of catheter-induced left main coronary artery spasm in a young woman is presented.
- The spasm was identified during a diagnostic cardiac catheterization.
- Symptoms included chest discomfort suggestive of acute coronary syndrome.
Findings:
- Intracoronary administration of nitroglycerin rapidly resolved the observed coronary artery spasm.
- Hemodynamic parameters and electrocardiographic changes normalized post-treatment.
- The spasm was definitively diagnosed through characteristic angiographic findings.
Implications:
- This case highlights the importance of recognizing catheter-induced coronary artery spasm.
- Timely intervention with intracoronary nitroglycerin can effectively manage this complication.
- Avoiding unnecessary coronary artery bypass graft surgery through prompt diagnosis and treatment is demonstrated.
Related Concept Videos
Cardiac Catheterization III: Left Heart Catheterization
Cardiac Catheterization II: Right Heart Catheterization
Acute Coronary Syndrome I: Introduction
Coronary Artery Disease III: Clinical Manifestations
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Cardiac Catheterization I: Pre-Procedure Overview

