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Published on: July 28, 2020
Aggressive repeat surgery for a recurrent synovial sarcoma in the pleura
Noritoshi Nishiyama1, Takashi Iwata, Nobuhiro Izumi
1Department of Thoracic Surgery, Osaka City University, Osaka, Japan.
Summary
This case report highlights aggressive repeat surgery for recurrent pleural synovial sarcoma. Aggressive tumor reduction followed by radiotherapy may control local disease in selected patients.
Area of Science:
- Oncology
- Thoracic Surgery
Background:
- Pleural synovial sarcoma is an extremely rare malignancy.
- Only 21 surgical cases have been previously reported worldwide.
Observation:
- A 31-year-old female presented with recurrent left pleural synovial sarcoma after initial resection and chemotherapy.
- Rapid tumor growth occupied the left hemithorax, necessitating a left pneumonectomy.
- Residual tumor around the descending aorta was treated with external radiation therapy.
Findings:
- Pathological examination confirmed recurrent monophasic synovial sarcoma.
- The patient remained ambulatory with no evidence of disease recurrence at 6 months post-surgery.
- This aggressive repeat surgery approach has not been previously reported.
Implications:
- Aggressive tumor reduction combined with radiotherapy can achieve good local disease control for recurrent pleural synovial sarcoma.
- Repeat aggressive surgery may be considered in select cases with insufficient chemotherapy response and difficult complete resection.
- Further research is needed to establish optimal treatment strategies for this rare cancer.
