Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sciatica management: chemonucleolysis vs. surgical discectomy.

F E LeBlanc

    Today'S OR Nurse
    |September 1, 1991
    PubMed
    Summary

    Sciatica and back pain result from lumbar nerve root compression. Chemonucleolysis and lumbar microdiscectomy offer effective surgical and non-surgical treatment options for pain relief.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Choroidal melanoma metastasis as a rare cause of cerebellopontine angle lesion: 2 case reports.

    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes·1998
    Same author

    Mapping of neural activity patterns using intrinsic optical signals: from isolated brain preparations to the intact human brain.

    Advances in experimental medicine and biology·1993
    Same author

    Sciatica: management by chemonucleolysis vs. surgical discectomy.

    Orthopedics·1991
    Same author

    Sciatica--management by chemonucleolysis versus surgical discectomy.

    Neurosurgical review·1986
    Same author

    Relaxation of bovine, porcine and human brain arteries by parathyroid hormone.

    Life sciences·1983
    Same author

    Acromegaly with an adenomatous pharyngeal pituitary.

    JAMA·1980

    Area of Science:

    • Neurosurgery
    • Orthopedic Surgery
    • Pain Management

    Background:

    • Sciatica and associated back pain are frequently caused by lumbar nerve root compression.
    • Two primary therapeutic strategies address this condition: surgical intervention and chemonucleolysis.

    Purpose of the Study:

    • To compare the efficacy of chemonucleolysis and lumbar microdiscectomy for treating sciatica and lumbar nerve root compression.

    Main Methods:

    • Chemonucleolysis involves intradiscal injection of chymopapain, a proteolytic enzyme.
    • Lumbar microdiscectomy is a surgical procedure to relieve nerve root compression.

    Main Results:

    • Chemonucleolysis shows a 75% success rate at 6 weeks and 80% at 6 months.
    • Lumbar microdiscectomy demonstrates an 85% effectiveness rate at 3 months.

    Conclusions:

    • Both chemonucleolysis and lumbar microdiscectomy are effective treatments for lumbar nerve root compression.
    • Treatment outcomes vary in terms of short-term and long-term efficacy.

    Related Experiment Videos