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Early infant feeding and type 1 diabetes
Erkki Savilahti1, Kristiina M Saarinen
1Hospital for Children and Adolescents, University of Helsinki, P.O.B. 281, 00029 HUS, Helsinki, Finland. erkki.savilahti@hus.fi
European Journal of Nutrition
|March 6, 2009
Summary
Early cow's milk formula feeding in infancy was not associated with an increased risk of type 1 diabetes. In fact, it may even reduce the incidence of type 1 diabetes before age 8.
Area of Science:
- Pediatrics
- Immunology
- Endocrinology
Background:
- Infant feeding practices, particularly milk type, are linked to type 1 diabetes development.
- Understanding early nutrition's role is crucial for preventing autoimmune diseases.
Purpose of the Study:
- To investigate the association between early infant feeding (first year) and type 1 diabetes risk.
- To analyze the impact of cow's milk exposure on diabetes incidence in a large cohort.
Main Methods:
- A population-based cohort of 6,209 newborns was prospectively followed.
- Infant feeding data, including formula type and duration, were collected.
- Diabetes status was ascertained through a nationwide registry until August 2006.
Main Results:
- No increased risk of type 1 diabetes was observed with early cow's milk-based formula exposure.
- Children exposed to cow's milk formula showed a trend towards lower type 1 diabetes risk (OR 0.66).
- This protective association was more pronounced before age 8, but not statistically significant by the end of follow-up.
Conclusions:
- Very early cow's milk exposure is not a risk factor for type 1 diabetes.
- Early cow's milk formula feeding may potentially decrease type 1 diabetes incidence before age 8.
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