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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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Pulmonary Tuberculosis I

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
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Updated: Jun 25, 2026

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test

Published on: April 9, 2012

Universal tuberculosis screening in pregnancy.

Nadav Schwartz¹, Sarah A Wagner, Sean M Keeler

¹Department of Obstetrics and Gynecology, NYU School of Medicine, New York, New York 10016, USA. nadavmd@hotmail.com

American Journal of Perinatology

|March 6, 2009

Summary

This summary is machine-generated.

Universal tuberculosis screening in pregnant individuals shows high compliance (95%) for purified protein derivative (PPD) testing. This approach effectively identifies latent TB but not active disease in this population.

Related Experiment Videos

Last Updated: Jun 25, 2026

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test

Published on: April 9, 2012

Area of Science:

Public Health
Infectious Disease Epidemiology
Maternal Health

Background:

Tuberculosis (TB) screening is crucial in at-risk populations.
Prenatal care offers a unique opportunity for universal TB screening.
Understanding compliance and yield is essential for optimizing screening protocols.

Purpose of the Study:

To evaluate the utility and patient compliance of universal tuberculosis (TB) screening in an at-risk pregnant population.
To determine the prevalence of latent TB infection (LTBI) and active TB disease in this cohort.
To identify demographic factors associated with TB screening compliance.

Main Methods:

Retrospective analysis of the Gouverneur Healthcare Services prenatal database.
Inclusion of 4049 pregnant patients undergoing universal TB screening.
Analysis of demographic data (age, ethnicity, country of origin, education) and screening compliance (purified protein derivative [PPD] testing and chest X-ray [CXR]).

Main Results:

95.0% compliance with PPD testing was observed.
Universal screening identified 50.4% of patients as PPD-positive (PPD+).
Chest X-rays (CXR) were available for 95.1% of PPD+ patients, revealing only one case consistent with active TB (sputum negative).
Asian women demonstrated higher PPD and CXR compliance compared to U.S.-born women.

Conclusions:

Universal prenatal TB screening is highly effective in identifying latent TB infection (LTBI) in at-risk pregnant populations.
Excellent compliance rates support the utility of this screening strategy.
The screening identifies a high prevalence of LTBI but is not effective for detecting active TB disease.