Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...

Cholesterol: Significance and Regulation

Cholesterol: Significance and Regulation

Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...

Disorders of the Nervous Tissue

Disorders of the Nervous Tissue

Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...

Depressive Disorders: Etiology

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...

Human Genetics

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Self harm: suturing of lips.

Revista espanola de sanidad penitenciaria·2021

Same author

Role of sCD40L in the prediction of super-response to cardiac resynchronization therapy.

Anales del sistema sanitario de Navarra·2021

Same author

Intervention protocol to improve scabies control in enclosed communities: a case report.

Revista espanola de sanidad penitenciaria·2021

Same author

Inmate carrier of cutis verticis gyrata

Revista espanola de sanidad penitenciaria·2019

Same author

Treatment of Chronic Lower Extremity Ulcers with A New Er:Yag Laser Technology.

Laser therapy·2017

Same author

[Patients with vulnerable coronary plaques have higher serum metalloproteinase-1 levels].

Anales del sistema sanitario de Navarra·2017

Search research articles

Related Experiment Video

Updated: Jun 25, 2026

Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol

Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol

Published on: March 25, 2020

[Relation between cholesterol levels and neuropsychiatric disorders].

P A Martínez-Carpio¹, J Barba, A Bedoya-Del Campillo

¹Centro Penitenciario de Jóvenes de Barcelona, Generalitat de Catalunya, Sant Joan de Déu, Barcelona, España. pmc@investilaser.com

Revista De Neurologia

|March 6, 2009

Summary

Low serum cholesterol levels are linked to increased risks of neuropsychiatric disorders, including suicide, aggression, and dementia. Further research is needed to confirm these associations between hypocholesterolemia and brain health.

More Related Videos

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

Derivation, Expansion, Cryopreservation and Characterization of Brain Microvascular Endothelial Cells from Human Induced Pluripotent Stem Cells

Derivation, Expansion, Cryopreservation and Characterization of Brain Microvascular Endothelial Cells from Human Induced Pluripotent Stem Cells

Published on: November 19, 2020

Related Experiment Videos

Last Updated: Jun 25, 2026

Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol

Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol

Published on: March 25, 2020

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

Derivation, Expansion, Cryopreservation and Characterization of Brain Microvascular Endothelial Cells from Human Induced Pluripotent Stem Cells

Derivation, Expansion, Cryopreservation and Characterization of Brain Microvascular Endothelial Cells from Human Induced Pluripotent Stem Cells

Published on: November 19, 2020

Area of Science:

Neuroscience
Psychiatry
Biochemistry

Context:

Recent surveys question the link between low cholesterol and neuropsychiatric conditions.
Emerging scientific evidence suggests a connection between reduced cholesterol and brain disorders.

Purpose:

To systematically review literature on the relationship between low serum cholesterol and neuropsychiatric disorders.
To analyze existing studies using statistical and critical-deductive methods.

Summary:

Low serum cholesterol is associated with various neuropsychiatric disorders.
Hypocholesterolemia may correlate with higher rates of early death, suicide, aggression, personality disorders, depression, and dementia.
Evidence suggests a particular link in young males.

Impact:

Highlights the potential neurological implications of hypocholesterolemia.
Underscores the need for further investigation into cholesterol's role in brain health.
Informs clinical practice and future research directions in neuropsychiatry.