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Related Experiment Video

Updated: Jun 25, 2026

Experimental Demyelination and Remyelination of Murine Spinal Cord by Focal Injection of Lysolecithin

Experimental Demyelination and Remyelination of Murine Spinal Cord by Focal Injection of Lysolecithin

Published on: March 26, 2015

Tumefactive demyelination.

M Y Nadkar¹, R A Deore, Raminder Singh

¹Dept. of Medicine, Seth G S Medical College and KEM Hospital, Parel, Mumbai 400012.

The Journal of the Association of Physicians of India

|March 7, 2009

Summary

This summary is machine-generated.

A young woman with a history of tuberculosis developed neurological symptoms. Magnetic resonance imaging (MRI) confirmed tumefactive demyelination, a rare condition, which improved with steroid treatment.

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Area of Science:

Neurology
Radiology
Infectious Diseases

Background:

Tuberculosis (TB) can have diverse neurological manifestations.
Tuberculomas and tuberculous meningitis are known complications of TB.

Observation:

A 22-year-old female with a history of pulmonary TB, tuberculous meningitis, and tuberculomas presented with right hemiparesis and altered sensorium.
Typical magnetic resonance imaging (MRI) findings suggested tumefactive demyelination.

Findings:

The patient's presentation mimicked neurological sequelae of prior tuberculosis.
Tumefactive demyelination was diagnosed based on characteristic MRI features.
The patient demonstrated a positive clinical response to corticosteroid therapy.

Implications:

This case highlights the importance of considering tumefactive demyelination in patients with a history of tuberculosis presenting with focal neurological deficits.
Early diagnosis and treatment with steroids can lead to favorable outcomes in tumefactive demyelination.
The differential diagnosis of neurological complications in TB patients should include demyelinating disorders.