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Related Concept Videos

Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
Cardiomyopathy VI: Nursing Management01:29

Cardiomyopathy VI: Nursing Management

Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...

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Updated: Jun 25, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
10:08

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine

Published on: February 17, 2018

Takotsubo cardiomyopathy.

James C Coons1, Megan Barnes, Karissa Kusick

  • 1Allegheny General Hospital, 320 East North Avenue, Pittsburgh, PA 15212, USA. jcoons@wpahs.org

American Journal of Health-System Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
|March 7, 2009
PubMed
Summary
This summary is machine-generated.

Takotsubo cardiomyopathy, a stress-induced heart condition, mimics heart attacks but lacks coronary artery disease. It presents with a distinct LV shape and requires specific management, avoiding certain medications.

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Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
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A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
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A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo

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Area of Science:

  • Cardiology
  • Cardiovascular Medicine

Background:

  • Takotsubo cardiomyopathy (TTC) is a condition mimicking acute coronary syndrome (ACS).
  • It affects patients experiencing significant emotional or physical stress.
  • TTC is characterized by transient left ventricular (LV) apical akinesis or dyskinesis without obstructive coronary artery disease (CAD).

Observation:

  • TTC presents with a hallmark "takotsubo" or "octopus trap" shape of the LV.
  • Symptoms often resemble myocardial infarction (MI), including chest pain and dyspnea.
  • Cardiac biomarkers like troponin may show mild elevations.

Findings:

  • The LV apex balloons outward while the base maintains systolic function.
  • Estimated to occur in 0.5-2% of patients presenting with ACS symptoms.
  • A case study illustrates diagnosis in a patient with ST-elevation MI symptoms.

Implications:

  • TTC serves as a crucial alternative diagnosis to ACS in specific patient populations.
  • Management focuses on supportive care, potentially including diuretics and vasodilators.
  • Vasopressors and inotropes are generally avoided due to potential catecholamine surge.