The management of renal angiomyolipomas in a patient with tuberous sclerosis

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Published on: June 15, 2020

Ilene Y Wong1, Linda D Shortliffe

  • 1Department of Urology, Stanford University School of Medicine, Stanford, CA 94305-5118, USA.

Nature Clinical Practice. Urology
|March 7, 2009
PubMed

Insights

Tuberous sclerosis can cause large bilateral renal angiomyolipomas. This case highlights observation and embolization as management strategies for these tumors.

Area of Science:

  • Nephrology
  • Oncology
  • Genetics

Background:

  • Tuberous sclerosis is a genetic disorder.
  • It can lead to the development of tumors in various organs, including the kidneys.

Observation:

  • A 17-year-old female with tuberous sclerosis presented with multiple bilateral renal masses.
  • The largest mass measured 6.0 cm in diameter on the left side.
  • Diagnostic workup included physical examination, ultrasonography, MRI, CT, and magnetic resonance angiography.

Findings:

  • Bilateral renal angiomyolipomas were diagnosed.
  • Serial creatinine levels were monitored.

Implications:

  • Management involved observation, serial imaging, and embolization with infarction.
  • This case underscores the importance of vigilant monitoring and tailored treatment for renal angiomyolipomas in patients with tuberous sclerosis.
Abstract

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