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Biological structures imaged in a hybrid scanning transmission electron microscope and scanning tunneling microscope
A Stemmer1, R Reichelt, R Wyss
1M.E. Müller Institute for High Resolution Electron Microscopy University of Basel, Switzerland.
Ultramicroscopy
|June 1, 1991
Abstract:
A hybrid scanning transmission electron microscope (STEM) and scanning tunneling microscope (STM) is described which allows simultaneous imaging of biological structures adsorbed to electron-transparent specimen supports in both modes of scanning microscopy, as demonstrated on uncoated phage T4 polyheads. We further discuss the reproducibility and validity of height data obtained from STM topographs of biomacromolecules and present raw data from topographs of freeze-dried, metal-coated nuclear envelopes from Xenopus laevis oocytes.