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Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation

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Published on: November 17, 2014

Corneal transplant surgery.

Karen McColgan¹

¹School of Nursing and Midwifery, Queen's University Belfast, Medical Biology Centre, Lisburn Road, Belfast, BT9 7BL. k.mccolgan@qub.ac.uk

Journal of Perioperative Practice

|March 10, 2009

Summary

Corneal disease causes worldwide blindness. This paper reviews corneal transplant options, including traditional penetrating keratoplasty (PK) and alternatives like deep anterior lamellar keratoplasty (DALK), deep lamellar endothelial keratoplasty (DLEK), and limbal stem cell transplant for vision restoration.

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Corneal Donor Tissue Preparation for Endothelial Keratoplasty

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Published on: June 12, 2012

Area of Science:

Ophthalmology
Regenerative Medicine

Background:

Corneal disease is a leading cause of global blindness.
Corneal transplantation is often the only effective treatment for vision restoration.

Purpose of the Study:

To discuss various corneal transplant surgical techniques.
To provide an overview of alternatives to traditional penetrating keratoplasty (PK).

Main Methods:

Review of established and alternative corneal transplant procedures.
Discussion includes penetrating keratoplasty (PK).
Exploration of deep anterior lamellar keratoplasty (DALK), deep lamellar endothelial keratoplasty (DLEK), and limbal stem cell transplant.

Main Results:

Penetrating keratoplasty (PK) is a traditional full-thickness transplant.
DALK, DLEK, and limbal stem cell transplant offer alternative approaches.
These alternative techniques may provide options for specific types of corneal damage.

Conclusions:

Various surgical techniques exist for corneal transplantation.
Alternative methods like DALK, DLEK, and limbal stem cell transplant are important considerations.
These advanced techniques aim to improve outcomes for patients with corneal disease.