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Updated: Jun 25, 2026

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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Dermatofibrosarcoma protuberans of the breast
Jong-Yueh Lin1, Shyr-Ming Sheen-Chen, Wayne Hsu
1Department of Surgery, Chang Gung Memorial Hospital, Kaohsiung Medical Center College of Medicine, Chang Gung University, Niao-Sung Hsiang, Kaohsiung Hsien, Taiwan.
Tumori
|March 10, 2009
Summary
Dermatofibrosarcoma protuberans is a rare breast tumor. Early recognition of this uncommon entity is crucial for effective diagnosis and management of this locally aggressive cancer.
Area of Science:
- Oncology
- Dermatopathology
Background:
- Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive skin tumor.
- DFSP typically affects the trunk and extremities, with breast involvement being exceptionally uncommon.
Observation:
- A 49-year-old woman presented with a long-standing, progressively enlarging right breast mass.
- Physical examination revealed a 2 cm firm, mobile, erythematous mass. Sonography indicated a dermal lesion.
Findings:
- Histopathological examination showed a hypercellular tumor of spindle cells with storiform patterns.
- Tumor cells exhibited strong CD34 immunoreactivity, confirming the diagnosis of DFSP.
Implications:
- This case highlights the existence of DFSP in the breast, despite its rarity.
- Increased awareness of DFSP can lead to earlier diagnosis and appropriate management of this challenging tumor.
