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Updated: Jun 25, 2026

Method to Visualize and Analyze Membrane Interacting Proteins by Transmission Electron Microscopy
Published on: March 5, 2017
Prokaryotic and eukaryotic integral membrane proteins have similar architecture
Rajneesh Kumar Gaur1, Girija Arun Natekar
1Redox Biology Center, N118 Beadle Center, University of Nebraska, Lincoln, NE 68588-0662, USA. meetgaur@gmail.com
Abstract:
Integral membrane proteins constitute a major constituent of lipid bilayer both in prokaryotes and eukaryotes. The statistical analysis was carried out to determine the bias in amino acid distribution between prokaryotic and eukaryotic integral membrane proteins (pIntMPs and eIntMPs). Our results indicate that both pIntMPs and eIntMPs demonstrate the striking similarity in amino acid distribution in their transmembrane and extramembranous region. pIntMPs have relatively greater functional importance for Gly and Asn in comparison to eIntMPs.
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