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Relationship between adiponectin, inflammatory markers and obesity in type 2 diabetic and non-diabetic Trinidadians
Shivananda Nayak1, Stephanie Quan Soon, Ryan Kunjal
1University of the West Indies, Champs Fleurs, Trinidad and Tobago. shiv25@gmail.com
Aim:
To determine and study the relationship between adiponectin and inflammatory markers in obese, non-obese, type 2 diabetic and non-diabetic Trinidadians.
Methods:
It was a cross-sectional study comprised of 133 subjects of Trinidadians. Anthropometric indices were measured and adiponectin, inflammatory marker levels, lipid profiles and glucose were measured in fasting blood samples.
Results:
Adiponectin levels were significantly lower (P = 0.003) in diabetics (n = 60) than non diabetics (n = 73). No correlation between adiponectin and inflammatory markers was found. Adiponectin levels were negatively correlated with BMI adjusting for age and diabetic status, and gender (beta = -0.200, P = 0.020; beta = -0.235, P = 0.004).
Conclusions:
No correlation exists between adiponectin and inflammatory markers. Adiponectin levels are lower in type 2 diabetic Trinidadians than in non-diabetics and decreases with increasing adiposity, using BMI as the marker.
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