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Related Concept Videos

Male Sexual Response: Erection & Ejaculation01:17

Male Sexual Response: Erection & Ejaculation

Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
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Neural Regulation01:37

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The Micturition Reflex01:26

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Regulation of Hormone Secretion01:19

Regulation of Hormone Secretion

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Neural Regulation of Blood Pressure01:18

Neural Regulation of Blood Pressure

The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
Baroreceptor Reflex
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Enteric Nervous System: Regulation of GI Motor Activity01:11

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Related Experiment Video

Updated: Jun 25, 2026

Dissection of Pelvic Autonomic Ganglia and Associated Nerves in Male and Female Rats
09:48

Dissection of Pelvic Autonomic Ganglia and Associated Nerves in Male and Female Rats

Published on: March 7, 2020

Neural regulation of ejaculation.

Brandt Young1, Lique Coolen, Kevin McKenna

  • 1Department of Physiology/Urology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA. bwyoung@northwestern.edu

The Journal of Sexual Medicine
|March 10, 2009
PubMed
Summary
This summary is machine-generated.

Lumbar spinothalamic (LSt) cells are key regulators of ejaculation. Further research into these "ejaculation generators" may lead to new treatments for male sexual dysfunction.

Related Experiment Videos

Last Updated: Jun 25, 2026

Dissection of Pelvic Autonomic Ganglia and Associated Nerves in Male and Female Rats
09:48

Dissection of Pelvic Autonomic Ganglia and Associated Nerves in Male and Female Rats

Published on: March 7, 2020

Area of Science:

  • Neuroscience
  • Urology
  • Sexual Medicine

Background:

  • Understanding the neurophysiology of ejaculation is vital for treating male sexual dysfunction, such as premature ejaculation.
  • Recent research implicates lumbar spinothalamic (LSt) cells in regulating the ejaculatory response.
  • LSt cell activation markers correlate highly with ejaculation and are absent during other sexual behaviors.

Purpose of the Study:

  • To review current knowledge on the role of LSt cells in regulating and generating ejaculatory behavior.
  • To outline future research directions for investigating LSt cell function in behavior.

Main Methods:

  • Comprehensive literature review of anatomical and physiological correlates of sexual behavior.
  • Extensive searches of PubMed using relevant keywords.
  • Analysis of clinical, anatomical, physiological, and behavioral data.

Main Results:

  • Evidence strongly suggests LSt cells are involved in ejaculatory behavior.
  • Targeted lesioning of LSt cells abolishes ejaculation.
  • Pharmacological studies are underway to further confirm LSt cell involvement.

Conclusions:

  • LSt cells function as a critical "ejaculation generator."
  • Further elucidation of LSt cells is crucial for developing treatments for male sexual dysfunction.
  • Ongoing studies aim to uncover the precise functions and mechanisms of LSt cells.