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Updated: Jun 25, 2026

Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture

Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture

Published on: November 25, 2025

Single and simple antibiotic prophylaxis for elective cholecystectomy.

Sikandar Ali Malik¹, Malik Amjad Yasin, Ghazala Nasreen

¹Department of General Surgery, Military Hospital, Rawalpindi.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

|March 10, 2009

Summary

A single antibiotic prophylaxis, like Gentamycin, is effective for open elective cholecystectomy, showing a low infection rate of 4.3% when strict sterilization is maintained.

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Last Updated: Jun 25, 2026

Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture

Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture

Published on: November 25, 2025

Area of Science:

Surgical Infection Prevention
Antibiotic Prophylaxis
Cholecystectomy Outcomes

Background:

Postoperative infection is a significant concern in open elective cholecystectomy.
Optimizing antibiotic prophylaxis protocols is crucial for patient safety and recovery.

Purpose of the Study:

To evaluate the effectiveness of a single, simple antibiotic regimen for infection prophylaxis in open elective cholecystectomy.
To determine the postoperative infection rate associated with this simplified prophylactic approach.

Main Methods:

A descriptive, quasi-experimental study involving 116 patients undergoing elective open cholecystectomy.
Exclusion criteria included acute cholecystitis, jaundice, and choledocholithiasis.
A two-dose regimen of Gentamycin was administered as prophylactic antibiotic, with emphasis on strict sterilization during surgery.

Main Results:

A low surgical site infection rate of 4.3% (5 out of 116 patients) was observed.
The majority of patients (95.7%) experienced a smooth postoperative recovery.
Identified pathogens in infected patients included E. coli (40%), Klebsiella (20%), and mixed growth (40%).

Conclusions:

Single antibiotic prophylaxis is a viable and recommended strategy for elective cholecystectomy.
Success is contingent upon the rigorous application of aseptic measures and sound surgical technique.
This approach can contribute to reduced postoperative infection rates in this surgical procedure.