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Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

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Related Experiment Video

Updated: Jun 25, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Spectrum of breast tuberculosis.

Shahida Parveen Afridi1, Aisha Memon, Shafiq Ur Rehman

  • 1Department of Surgery, Dow University of Health Sciences, Civil Hospital, Karachi. drshahishakeel@yahoo.com

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|March 10, 2009
PubMed
Summary

Tuberculosis of the breast often mimics breast cancer and requires tissue diagnosis for differentiation. Surgical intervention is frequently necessary, even with anti-tuberculosis treatment, for effective management of breast tuberculosis.

Related Experiment Videos

Last Updated: Jun 25, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Area of Science:

  • Infectious Diseases
  • Oncology
  • Surgical Pathology

Background:

  • Tuberculosis can affect the breast, presenting diagnostic challenges.
  • Differentiating breast tuberculosis from malignancy or granulomatous mastitis is crucial.

Purpose of the Study:

  • To define the clinical presentation of breast tuberculosis.
  • To evaluate diagnostic modalities for breast tuberculosis.
  • To assess surgical treatment outcomes for breast tuberculosis.

Main Methods:

  • A case series of 30 patients diagnosed with breast tuberculosis.
  • Diagnostic work-up included clinical examination, imaging (ultrasound, mammogram), and laboratory tests (Mantoux, AFB smear/culture, FNAC).
  • Surgical interventions involved core biopsy or wide excision biopsy based on lump size, alongside anti-tuberculosis therapy.

Main Results:

  • The mean age of patients was 28.4 years, with multifocal disease in 27 patients.
  • Common presentations included discharging sinuses (14), cold abscesses (8), and lumps (6).
  • Surgical management was required in 70% of cases despite anti-tuberculosis treatment.

Conclusions:

  • Breast tuberculosis closely simulates breast carcinoma and granulomatous mastitis, necessitating tissue diagnosis.
  • Surgical intervention is often a required component of treatment for breast tuberculosis.